I highly recommend watching the documentary Zero days which is almost a decade old now, but about stuxnet.
It was mainly developed by Israel and the US specifically to target this very facility (natanz), and try to blow up nuclear centrifuges and slow down Iran's nuclear enrichment program.
The project failed (only managed to slow down their program for a few months) and was a prime case of blowback, since stuxnet infected critical infrastructure around the entire world, and even the US had to devote considerable resources protecting their systems from a virus they helped create.
I believe there's a pretty low chance of any meltdowns or nuclear events, due to so many fail-safes.