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2 yr. ago

  • The metric was that it is no more effective than placebo. It is a very old drug and was grandfathered in from a time before modern standards.

    The FDA was told this by researchers in 2007, but they wanted mOrE dAtA.

    Edit to add: It does have more effectiveness when used nasally as opposed to orally.

  • You're running local storage for a VM host? Or are you talking more like whiteboxing your own NAS?

    I understand what bcachefs does. I've used bcache many years ago to do exactly what you're describing, albeit for bare metal servers. I'm asking why.

    I'm just trying to understand what the use case would be in 2023 outside of a home lab, given that cost per gigabyte is basically at parity between SSDs and HDDs when you consider TCO (i.e. when you price in the extra power and cooling overhead for the HDDs, failure rates, and such).

  • This would have been really nice to have a decade ago. In the age of virtualization, what's the use case?

    EDIT: I'm not asking rhetorically. It really would have been nice to have 10 years ago for my use cases. What use cases do you envision for bcachefs in 2023?

  • And via a website too

    Everyone knows real admins do curl https://raw.githubusercontent.com/something/or/other/install.sh | sudo bash

  • People are inherently bad at rating things. Why not run a "This or that?" style study instead?

    Given a list of items to rate, pair them up randomly. Ask a person which item they like better out of each pair. Run through Final Four type eliminations until you get down to their number one preference.

    Run through this process for each person, beginning with different random pairings every time.

    Record data on all the choices - not just the final ones. You should be able to get good data like that.

    For example, there will probably be a thing that is so disliked that it gets eliminated in the first round more frequently than anything else. The inverse will likely be true of a highly-preferred item. And I am sure you can identify other insights as well.

  • If you can't get fresh, instant is fine

  • Another gem of the Internet: YouTube video IDs with actual dashes in them!

  • So were the Prophets, apparently. I bet Q felt their energy behind that punch and noped out of there.

  • No problem, hope it was helpful. I will review further when I have time.

  • It was a typo that has been corrected to AFAB. The edit may not have federated to your instance yet.

  • A typo. It should be AFAB, assigned female at birth.

  • I found these citations in a paper on the first page of Google. I apologize but I have not verified them.

    Fayyad J, De Graaf R, Kessler R, et al. Cross-national prevalence and correlates of adult attention-deficit/hyperactivity disorder. Br J Psychiatry. 2007;190(5):402–409.

    https://scholar.google.com/scholar_lookup?journal=Br+J+Psychiatry&title=Cross-national+prevalence+and+correlates+of+adult+attention-deficit/hyperactivity+disorder&author=J+Fayyad&author=R+De+Graaf&author=R+Kessler&volume=190&issue=5&publication_year=2007&pages=402-409&pmid=17470954&

    Retz W, Retz-Junginger P, Thome J, et al. Pharmacological treatment of adult ADHD in Europe. World J Biol Psychiatry. 2011;12(suppl 1):89–94.

    https://scholar.google.com/scholar_lookup?journal=World+J+Biol+Psychiatry&title=Pharmacological+treatment+of+adult+ADHD+in+Europe&author=W+Retz&author=P+Retz-Junginger&author=J+Thome&volume=12&issue=suppl+1&publication_year=2011&pages=89-94&pmid=21906003&

    Newcorn JH, Weiss M, Stein MA. The complexity of ADHD: diagnosis and treatment of the adult patient with comorbidities. CNS Spectr. 2007;12(suppl 12):1–14. quiz 15–16.

    https://scholar.google.com/scholar_lookup?journal=CNS+Spectr&title=The+complexity+of+ADHD:+diagnosis+and+treatment+of+the+adult+patient+with+comorbidities&author=JH+Newcorn&author=M+Weiss&author=MA+Stein&volume=12&issue=suppl+12&publication_year=2007&pages=1-14&

  • See the gear icon on the right? That's what it's there for.

  • We also used to call PTSD "shell shock" even though you don't have to go to war to be affected. Science and medicine change and improve over time.

  • The scientific, peer-reviewed answer is that it is significantly under-diagnosed in adults as well as in those AFAB of all ages. Most sources say up to 80% of adults with ADHD are undiagnosed and/or untreated.

  • So you're telling me Section 31 didn't scrub that ship clean before sending it off to be adapted into a museum exhibit? Let alone any other science team?

    My suspension of disbelief is stretched rather thinly with respect to the Tuvix flower being handed over to some lower deckers to be cargo on a California class before being put on rotating display to the public. It just seems way too dangerous to not end up going straight to either Daystrom.

    Still loved it though.

  • It's certainly one of the more fascinating versions of the trolley problem