I have started work on splitting up parts of the Sushi Train into smaller factories. The thing I liked about the Sushi Train was that if one of the assemblers/manufacturers/etc weren't producing anything anymore, then another could use the same building resource instead. That way you don't end up wasting ingot/ore production because the assemblers are idle. As an example, I have moved copper sheet, ingot and wire construction (mostly) next to the miner and each of the 3 can use 100% of the miners output. That way resources are only wasted if both constructors are idle and no ingots are needed elsewhere.
I think nuclear is one of my favorite parts of the game. The process for making it and then converting the uranium waste into plutonium is massive, but feels so rewarding once it's done. Thing is, I'm only running one plant at the moment since I still have enough power production from coal and geothermal. Figured it'd be best to keep plutonium waste to a minimum until I really start needing it, unless they add a feature to bury it. I've moved my plants next to the out-of-bounds area near Niagara Falls so I can store the plutonium waste in a container out-of-bounds.
The short but incorrect answer would be somewhere between 300-400 hours, but that's from the start of playing Satisfactory (as in, my first time playing this game) up to completing the last launch in the space elevator to get the golden mug. It also includes many nights of just leaving the game running. I originally started (with friends) in the flat grasslands and started moving a lot of production into the area you see in the video. A lot of the coal generators and things built on foundations (the stuff that looks neat) was built by friends.
Wow. Apparently, Satisfactory has been upgraded since I last played so I've got to go back and give it another play. Never thought to build that high! Never thought to connect one vertical conveyor to another! Too much 'thinking in the box' I guess.