I live in the southeast and work with snakes on the side (volunteer work and relocating them). Eastern Diamondbacks are a very defensive but nothing to worry about. Pygmy Rattlesnakes are the same way. Timber Rattlesnakes are the odd ball. They're placid to a fault. Overall, the same rules apply as with all North American snakes. Keep your distance, leave it alone, and you have nothing to worry about.