The sheer quantity of analytics from both Plex clients and servers, regardless of what options you select, is the number one blocked item on my Adguard Home install. Plex is, by no stretch of the imagination, not at all respectful of privacy.

Plex has sadly lost its way, and this year I finally switched over to Jellyfin and it's much better than the subsequent years I've tried to move across. Other than simplicity of exposing your server on the internet, Plex's value proposition has tanked.