Most people with a nas use the nas as storage and a mini pc like intel nuc or dell optiplex mff or other as server with dockers. Think a lot started with a nas only but moved on. Like a lot of people start with a PI for docker and move to a mini pc.
So it will be possible but you will maybe migrate after some time to a different setup.
My setup is an optiplex mff as little nas and server with dockers like sonarr, radarr, qbittorrent, etc.. running 24/7. Connected to my TV an optiplex mff with windows 10 to play jellyfin and other stuff.
Powerconsumption of an optiplex and nuc is also very low.