3w ago

Running rewires your brain cells—igniting memory-saving genes against alzheimer’s

www.sciencedaily.com Running rewires your brain cells—igniting memory-saving genes against alzheimer’s

Scientists have uncovered how exercise directly influences brain health in Alzheimer's disease by pinpointing the exact brain cells affected. Using cutting-edge RNA sequencing and mouse models, researchers identified changes in specific cells like microglia and a novel type of astrocyte after exerci...

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TL;DR: Fucking exercise, bro. So good. Am I right?
- I think the important part overall is cardio. You need to elevate your heart rate for sustained periods of time. Lifting weights is better than not, but your brain benefits from the increased and improved blood flow "to clean out the garbage" (much like quality sleep).
  
  My anxiety attacks elevate my heart rate daily. Does that count?
  
  Actually, it probably does. But the negative effects of anxiety probably outweigh it.
  
  Lol. I feel ya!
  
  It actually increases the risk of dementia: https://pmc.ncbi.nlm.nih.gov/articles/PMC7355582/
  Have you tried daily exercise, mindfulness, and anxiety-reducing supplements?
  
  Have you tried not having ADHD?
  
  is heartrate the deciding factor here? if so, my gooning sessions and horror games achieve that just as well
  
  the problem is just elevating your heartrate without exercise your body won't dilate your blood vessels to accommodate the faster blood traffic. This makes for lots more collisions between the blood cells and the intersections where blood vessels diverge, causing low grade damage to the system that builds up over time.
  When your muscles activate with your heart the blood vessels all dilate and the blood pumps much smoother.
  
  amateur
- No. Exercise SUCKS.
  Gotta do it, but in 65 years I have yet to find any exercise "good" or "fun" or "enjoyable" or "invigorating."
  When I force myself to do my workout it's walking at 135 steps/minute, 8% incline, and when I check my heart rate at the end of the 35 minutes it takes to do 3k, (I'm short with short legs) it's about 145. Running is not an option.
  It leaves me dripping with sweat and in a bad mood. I only do it because I have to. So don't give me that shit.
  
  So I'm a relatively young and healthy person. Im lucky enough to live in a city with an extensive parks system, and go hiking very regularly.
  I find that it's fun, enjoyable and invigorating because I'm outside, and there are things to see. As a result, the fact that it's exercise becomes secondary.
  How are you excercising? Because if it's going to a gym, or walking on a machine... Yeah I'd be miserable too.
  
  This. No matter how much I do it, I never get that "invigorated" feeling people talk about.
  I always end up just feeling like shit and, because of my CMT, I take longer to recover. What may take a normal person a few hours to recover from will take me an entire day. My normal is being constantly fatigued, exercising just exacerbates it. Hell, not to even mention that my doctor even told me that running is not a good exercise for someone with my condition because of the inevitable atrophying of the extremities means that impact from my feet hitting the ground is damaging my joints.
  I'm also autistic and the sensory overload of being sticky from sweat and overheated from exertion literally makes me want to flay myself to escape my own skin.
  
  Yeah you should definitely avoid running. At a guess, maybe in-pool exercises would be less uncomfortable? Keep you cooler and balance out the skin sensations? But with fatigue issues you'll want to stay shallow enough to stand unless you're a good floater, and have someone near the pool just in case.
  Or is exercising something you should even be doing? Maybe you have a doctor's excuse!
  
  Doctor has advised "low impact" exercises such as swimming and cycling as alternatives
  Those would be good alternatives if I had access to them. No pool anywhere nearby and no infrastructure to cycle safely. Rural area is aggressively anti-cyclist. Like "people will run you off the road into the ditch for laughs" aggressively anti-cyclist. Too poor to afford stationary equipment, much less a home with a yard to put a pool.
  Even still, I'm fighting a losing battle. My body will atrophy no matter what I do. All any exercises will accomplish is slowing the degradation. Already have partial loss of use in my hands, haven't been able to play my guitar in over a decade now, and only a matter of time before I can no longer use my legs.
  
  No. Exercise SUCKS.
  Then don't "exercise". At least not formal workouts.
  One "life hack" for people who hate working out is simply to do more things manually.
  Errands? Walk or bike.
  Hungry? Prepare the meal from scratch.
  Laundry? Try handwashing.
  The idea is to move, and if possible, move enough to elevate your heartrate. Add resistance whenever possible.
  Of course, this is the bare minimum you can do for yourself. Doing more will bring greater benefits, but anything is better than just sitting in a car, at a desk, in front of a TV.
  And the more you do with consistency, the easier things get, and your body won't feel run down doing basic things.
- Always has been. Now imma sit here and not do any.

48 comments