'Cancer-killing pill' that appears to 'annihilate' solid tumours is now being tested on humans
'Cancer-killing pill' that appears to 'annihilate' solid tumours is now being tested on humans
"Our cancer-killing pill is like a snowstorm that closes a key airline hub, shutting down all flights in and out only in planes carrying cancer cells," says the professor who has been developing the new drug over the past 20 years.
yet another tool in oncologist toolbox, and looks like a pretty capable one. looks like it also has an effect of sensitizing cancer cells to other chemotherapy drugs
more technical writeup https://www.science.org/content/blog-post/new-mode-cancer-treatment
34This treatment looks to give us the ability to buy time. So many treatments just cannot act fast enough or are so weakening at higher doses that the person doesn't make it. I think we will see a lot of new treatment options that give us room for creativity when the first option fails. I've lost a lot of people I love to cancer in my life. I'm hopeful that those I love still living will be with us longer, so I can love and enjoy them more. At least until the next thing after cancer gets them (or me).
16we don't know yet, it might be very well a part of complete cure for some cases
and judging by mechanism which is pretty general, that might be a lot of cases and resistance may be hard to develop
1
This is the best summary I could come up with:
A "cancer-killing pill" has appeared to "annihilate" solid tumours in early research - leaving healthy cells unaffected.
Professor Linda Malkas, who has been developing the drug, explained: "PCNA is like a major airline terminal hub containing multiple plane gates.
"Our cancer-killing pill is like a snowstorm that closes a key airline hub, shutting down all flights in and out only in planes carrying cancer cells."
While initial results are promising, the research so far has only concluded that AOH1996 can suppress tumour growth in cell and animal models - with the first phase of a clinical trial in humans now under way.
The pill has been shown to be effective in treating cells derived from breast, prostate, brain, ovarian, cervical, skin and lung cancers.
PCNA had previously been labelled as "undruggable" - and it is hoped the breakthrough could lead to more personalised, targeted medicines for cancer in the future.
I'm a bot and I'm open source!
30Looks like a treatment, not a cure, that will require ongoing supplies of medication. This is a pharma wet dream. We can’t cure your cancer, but we can keep it from growing for just $2000 per pill that cost us $1 to make.
22Do you really think that pill cost 1$? A single approved therapy takes years to develop and over a billion dollars. But hey if you're view of an entire industry is shaped through Facebook comments I don't blame you.
Further, maintenance therapy already exists in many cancers. This is not a new concept for literally anyone in the field of medicine.
21At the moment, it doesn’t look like anything, since it’s just now in phase 1 trials, so nobody knows.
But if it does what it says, then yes, it might actually be part of a cure.
And I don’t know if you’re aware of it, as of now we don’t have a cure for cancer: https://xkcd.com/931/
You can look up the average treatment cost today, it’s something like $150000, good for your that you already know the price of this pill and that it’s big pharma‘s wet dream.
14"Why don't they just cure cancer!"
🙄
12Permanently Deleted
2Where are you getting this information? Every other form of chemotherapy is a limited course, and I've seen no evidence that this one is any different.
1
Heard about this on the radio yesterday, and looked into it further as we hear about “cancer curing pills” all the time and they usually are nothing. This one does seem to have traction however IF it can make it through human trials. So obviously could mean nothing if it doesn’t pass this phase, and it will be there a long time, but this is very promising news.
16Good to see this pill be created. Very nice.
13I just created the summary! You can find it at https://lemmings.world/comment/894209. (I tried to create the link for your instance but I failed miserably, for which I'm very sorry).
2
Another way for the new world order to kill the population.
-4Joe Brandon filling his campaign promise /s
But it is good to see more treatment options
-5Maybe conservatives will treat this medical advancement the same as other medical advancements. To be fair, these pills are obviously loaded with 5G tracking chips and are clearly not as effective against cancer as horse dewormer or bleach.
7