[Lecture] From fibre to the microbiome: low carb gut health - MD Mason

Papers referenced

Constipation

When we look at the best evidence available fiber worsens constipation, causes bloating, and does absolutely nothing to moisten our feces.

• Myths and Misconceptions About Constipation: A New View for the 2020s
• Stopping or reducing dietary fiber intake reduces constipation and its associated symptoms
• Water-holding by dietary fibre in vitro and its relationship to faecal output in man

Short Chain Fatty Acids

• Diet rapidly and reproducibly alters the human gut microbiome
• Beneficial Effects of High Dietary Fiber Intake in Patients with Type 2 Diabetes Mellitus
• Effect of a High-Protein, Low-Carbohydrate Diet on Blood Glucose Control in People With Type 2 Diabetes

FODMAPS

• Methanogens, methane and gastrointestinal motility
• Fructan, Rather Than Gluten, Induces Symptoms in Patients With Self-Reported Non-Celiac Gluten Sensitivity
• Irritable Bowel Syndrome

Microbiome

• Human gut microbes associated with obesity
• An obesity-associated gut microbiome with increased capacity for energy harvest
• Dietary trehalose enhances virulence of epidemic Clostridium difficile

Fibre is not a necessity for a healthy diet

The whole concept of altering our microbiome for weight loss is a bridge to far with our current understanding of science.