The Trump administration can go ahead and purge more than 1,600 research grants issued by National Science Foundation (NSF) worth more than $1bn, after a judge declined to grant a preliminary injunction in a case brought by a coalition of organizations representing thousands of scientists.

The NSF is the premier federal investor in basic and cutting-edge science and engineering, which until Trump’s second term enjoyed bipartisan support, with the agency’s independent review process revered globally as the gold standard.