I can't believe I'm spending time providing a serious answer to this nonsense question, but here goes.
Yes. Obviously yes. At least assuming the bullet survived out of the gun.
Tylenol is a pain killer, but it's not a magic videogame pill. Its effects are nowhere near strong enough to overcome the pain of being shot. And even if they were, it still takes time to be absorbed.
Your best hope is that the Tylenol pill is too fragile and it breaks up within the gun, leaving a large number of small, light particles of Tylenol flying at you, which will get decelerated much more quickly by air resistance than would a single solid pill.
Assuming the mass is equivalent between a Tylenol bullet, and a Tylenol extra strength bullet. They would do the same damage on impact. Force equals mass times acceleration.
Every impact of a high speed accelerated object will hurt. Even a bullet made of hydromorphone (one of the strongest pain killers) or lidocaine (local anesthetic) will hurt long before the active agent has any chance to do its thing.