Which job(s) would you refuse to accept regardless of how good the pay is?

ICE agent.

What if they paid you enough to bankroll a political campaign for the opposition?
- A) they wouldn't. B) I'd still end up in jail for attacking another agent.
Unless you are very good at causing internal disruptions, sabotage and slow downs.
Same. Although mainly because I don't have the cool maintain my cover while undermining the organization from within.
- I'd end up with assault/murder charges, for tasing/shooting one of the bulldogs.
But, what about your monthly "nut"?
- I'll stick with growing weed and building computers. Less blood on my hands there.

ICE thug Slumlord’s handyman Anything that takes orders directly from the Trump administration

ICE

Hmm, you sure? You should watch South Park, S27, E2.
Might change your mind. 😉

Raytheon and co. Anything related to "defense", really.

You only go around the sun so many times, and you want to spend it on making brown kids into skeletons more efficiently? Fuck that shit.

Everyone just saying jobs they dont like, or that they have ethical qualms about, but ignoring "regardless of pay" - and I don't believe you.

Just imagine the salary for the position is $500m per year. At a certain point, you would be able to quit the job with plenty of money for the rest of your life after working for a very short period of time, or else you would be able to use the money to make more good in the world than the harm done by your labor.

If you have a skill set someone is offering $500k for, someone less shitty is going to be offering at least $400k. So you're not giving up $500k, you're giving up $100k or 20%. I've taken bigger pay cuts than that in exchange for increased job satisfaction.
- Every other job will only hire you for a normal wage that you would make in the real world.
  The point of the exercise is to grapple with an ethical quandry, not to sidestep it.

My coworker left our job because a place offered him a pay raise that was like half his current salary.

He came back - the job was so terrible he couldn't stay there. Not just the actual work, but the people.

I try to avoid working anyplace evil, so banks, oil companies, etc. and there are environments I can't be productive in - government, healthcare, anyplace very structured and bureaucratic. I guess if the pay and position are secured, and I can handle my work however I want without losing them, then I would not do anything that would kill me or others either directly or through incompetence (underwater welder, race car driver, assassin, surgeon), would probably cave on banks and other evil orgs, since I might be able to try to change them from the inside.

I try to avoid working anyplace evil, so banks, oil companies, etc. and there are environments I can’t be productive in - government, healthcare, anyplace very structured and bureaucratic.
That's who invented the Internet.
I work for a Contractor who contracts to Government, including Healthcare. The job is meh, but the people are absolutely awesome. The structure is actually a huge benefit, and it makes all the dotcoms' seat-of-the-pants I.T stand out so much more. There's no power-play to prevent updating software - for example - just because "Doug knows the CEO and he doesn't want to" because Dougie's written objection wouldn't pass scrutiny -- and, at most, Doug would get an extension to follow a set plan with milestones to get to that update anyway. But there are many examples where common dotcom slackery dies under review.
There are obvious and well-repeated problems with the overly-structured setup, but they're different from the ones that bother me, and erring on the side of safety and most-benefit is what annoys people ("why can't we have containers and supply-chain exploits like everyone elssssse") the most.
- I tried to work in a structured and bureaucratic environment once and was so useless because I want to change everything all the time, and wasn't used to "have your manager talk to her manager", or people trying to blame their errors on others, or trying to get their job. When I saw the lady who did payroll checking everyone off on a long sheet of green and white paper even though they were paying for Kronos and just not using it right, but she protected her job and didn't want it to change, and people there would make others look bad instead of helping them, in an effort to look better themselves in comparison, I cannot function in that world.
  I've only worked at startups, and the good part of that is that everyone is trying to do things better, easier, I don't get mad if someone sees a better way I could do something, and they don't have to have their manager tell my manager. And everyone helps everyone, nobody is protecting their job because there is always too much, helping others is how you move up here.
  (And yes I know this is a personal difference, not saying it's a better work environment for everyone, or even better for results. Accounting is its own type of work, too - I try to solve problems and get the software to do what a machine does better than a person. The kind of accounting where you are doing what a machine can, is dreadfully boring. I have often thought help desk at my work is the best job. They troubleshoot, and set up equipment, it's got a good balance of work. )
There are pipeline and mining jobs near me that would leverage my degree and skills but I don’t even entertain applying, I would hate it there doing stuff I feel is wrong.

"By the way, if anyone here is in advertising or marketing...kill yourself" --Bill Hicks

"Oh, you know what Bill’s doing? He’s going for that anti-marketing dollar. That’s a good market. He’s very smart."
- No! Fuck you, you work in advertising you’re sucking the devils cock. Kill yourself!
I worked in marketing. Though..
I create materials/tools to help patients with chronic diseases stay adherent to medication while building a better lifestyle
I made materials to convince health insurance companies to cover medications
So, it's not all bad. I moved on to hospital records analysis to identify things that would kill people, and now work in protocols and systems that help preserve the privacy of user data (one of them even uses ActivityPub).
I've been pretty fortunate in the jobs I've been able to find.
- "Look, I've worked with other vulture companies to convince them to get better PR by not being absolute soul-rotting evil all the time!" is not the flex you think it is, R.E. insurance compainies.

Palantir